SUMMARY: We’re excited to be presenting what the evidence finds for WHAT TO EAT, and WHAT NOT TO EAT, for BRAIN HEALTH! We will be at the beautiful Blue Ridge Region for the 2019 Virginia Council of Nurse Practitioner (VCNP) Annual Conference! IN the meantime, you win too because we decided to share a bonus here –>\0/ the prelude videoto our presentation, which is called “Add 7.5 yrs to Brainspan with MIND diet and SAGE Cognition Assessment Tool”. We also want to let you know that your response has been overwhelming for wanting us to bring our DIET, DEMENTIA, COGNITION, ALZHEIMER’S presentation to you! We’re here to dispel the brain age MYTH –> Those in their 40s and 50s realize that brain changes are occurring in the midlife time-frame. By 2050, 20% of the US population will be over age 65. One fifth will have mild cognitive impairment, increasing risk of Alzheimer’s. The Western diet is aging the brain faster than the Mediterranean diet as found on both MRI and PET imaging. You need to learn all about this! We’re booking now, so if you are interesting in having your group learn this powerful information, click here to contact us! And, just adding… they are also including our other Therapeutic Diet presentations for (1) Hypertension, Atherosclerosis, and Obesity, (2) IBS and Autoimmunity, and of course (3) Dementia, Cognition, and Alzheimer’s. You can learn about all of those programs here! Let’s hear from you today. Let’s move off DiseaseSpan and onto HealthSpan!
Tag Archives: CME_Microbiome
Brain, Cognition, Diet, CE (Nursing). March 2019 PRESENTATION!
SUMMARY: Our upcoming CE presentation at the 2019 Virginia Council of Nurse Practitioner (VCNP) Annual Conference, March 7th, dives deep into BRAIN, COGNITION, DIET, CE, ALZHEIMER’S! We are going to share what the evidence finds for WHAT TO EAT, and WHAT NOT TO EAT, for BRAIN HEALTH! Our presentation is called “Add 7.5 yrs to Brainspan with MIND diet and SAGE Cognition Assessment Tool”. What you need to know –> A LOT of research is looking at specific diets and brain health. At this time, the MIND diet rises to the top for reducing the risk of Alzheimer’s disease and cognitive impairment both with strict and moderate follow. It is this latter finding that makes the MIND diet BETTER than the Mediterranean and DASH diet for brain health because those had NO significant impact on AD risk reduction for moderate follow! ♥–> Diet has incredible systemic reach, including all the way to crossing the blood brain barrier! BAM–> Diet is perhaps the biggest determinant of the microbiome constituents. The major focus of recent research is on the microbiome and its by-products (called metabolites) because those can be changed up by diet and lifestyle. Thus diet can alter the microbiome towards health (anti-inflammatory) or towards being more disease-prone (inflammatory). \o/ If you are a Licensed Nurse Practitioner (in any state), or student enrolled in a NP program, plan to attend this Brain, Cognition, Diet CE! Those unable to attend, or not nurse practitioners, message us for information on how you too can see this presentation! \o/ The bottom line is that everyone needs to hear this information because recent studies find that eating a Western-style diet literally SHRINKS the brain, even in middle age. The results accounted for the effects of all other lifestyle factors, indicating that, when people are in their 40s and 50s,diet exerts a stronger influence on Alzheimer’s disease than exercise or intellectual activity do. “Alzheimer’s doesn’t just turn on when you reach a certain age,” explains Lisa Mosconi, PhD, associate director of the Alzheimer’s Prevention Clinic at Weill Cornell Medicine and NewYork-Presbyterian. “Instead, it’s a very long process that starts with changes in the brain when people are in their 40s and 50s. So we have a good 20 years to do something about it. The question is, what can we do in terms of prevention?” This Brain, Cognition, Diet, CE Alzheimer’s information is key to mitigating those risks! ♥
CME MICROBIOME Questions & Answers
Businesses (especially self insured) looking to reduce healthcare costs, can contact us too because microbiome information is what your employees NEED to hear to keep (or move) them off diseasespan. Individuals and other groups wanting to hear this information can also CONTACT us to make that happen! See here for our SERVICES!
CME MICROBIOME Questions & Answers
I’m on the ‘Avoid’ Diet. “What do you recommend I do to get off that diet?“
First, the ‘Avoid Diet’ is on my ending slide, shown below! Generally, it is associated with the most restrictive elimination diet, Wahl’s Protocol, having research including clinical trial for neurological based MS as well as grants written for study for Alzheimer’s Disease (AD) and ALS. I explained that ALL of the healing diets meld together in that they are =&0=&. David Katz, MD noted the same, Oct 2017, in “Awakening From Alzheimer’s”, Episode 11. Further, he explained that what we can ALL agree on resolves over 80 percent of the health concerns as shown by the North Karelia Project (Finland). Consider the ‘Avoid Diet’ tenets as food for thought when health isn’t restored. I totally ♥ this question because it shows that my presentation motivated this doc to rethink diet and instilled desire to act to get off the path leading to diseasespan! Patient microbiome awareness education nudges nearer, and that is so necessary!
“Don’t ever underestimate the public — the key issue is lack of knowledge about microbes, not lack of intelligence,”
—Ed Yong keynote, October’s 2017 MoBE.
My suggestions were:
- Quitting things cold turkey can be hard. I don’t recommend it!
- Try eliminating the bad by crowding it out with better alternatives!
- You cannot make the transition over night.
- The tools I provide really help! The Interactive Fiber Spreadsheet teaches what YOUR fiber loads are and especially those supporting your beasties. The EASY 10 Day Journal Spreadsheet teaches you what YOUR proportion of meats, dairy… and most important, processed and prepared foods are. Those usually contain gut harming emulsifiers [see this post], sweeteners, and other additives as well as low quality antibiotic and hormone laced meat and dairy protein and pesticide laced vegetables and fruits. The worksheet listings of vegs and fruits (Wahl’s Protocol and Dana-Farber Cancer Institute Phytonutrient PDF) helps you bump up your intake. Target 30 different vegs each week for microbiome diversity [see this post]. There are 21 meals in one week (3 each day). Think about eating a different vegetable or two at each meal!
- You can’t stop everything you are doing if you aren’t prepared to replace it with healthier alternatives. You need some recipes.
- I already armed you with a bank of recipes! Use my Pinterest Boards to learn what to eat and how to cook redic delic family and friend approved whole real microbiome friendly food. Focus on eliminating processed foods (having gut harming additives like emulsifiers) and increasing vegs!
- Certain vegs contain microbiota-accessible carbohydrates, or MACs, which nourish the beasties towards anti-inflammatory, and provides them food so that they don’t nosh on our carb-rich mucus gut lining, when dietary pickings get slim. [Desai et al 2016] The post, Fiber Additives Starve Gut Gut Microbes, They Eat Mucus Lining helps to explain.
- Contact me if recipes alone are not getting you where you want!
Healing Diet similarity
The top healing diets in each category share similar attributes including balance, higher vegetable and some fruit (especially low sugar like berries, avocados), wild caught fish/increased Omega-3s, fermented food, awareness of EWG toxin recommendations, along with self-awareness and monitoring of what you eat through journaling, and most important, finding a like-minded tribe of experienced healing diet eaters able to support your learning thereby establishing Blue Zones within families, to friends, to communities. =&1=& An emphasis on frequent, structured exercise and physical activity are also common themes.
With awareness of the many tenets of healing type diets and lifestyle impact on the microbiome, small diet and lifestyle changes result in big health improvement without the perceived rigidity of following a traditional diet plan, and these changes motivate you to your NEXT. – much is an excerpt from my post, What’s in a Practical Whole Foods PALEO, SCD, GAPS Healing Fridge?
Replicate the MODEL that WORKS for people successfully implementing diet change:
Experienced Eaters TEACH ‘Need to Know’ =&2=&
=&3=&
Optimal Microbiome Diet From American Gut Data
Microbiome and associated health problems
[Cantinean et al 2018], Figure 1 shows the link:
Table 1, lists links between several diseases and changes of microbiota:
Disease | Changes in microbiota’s diversity and composition | Consequences | Reference |
---|---|---|---|
Inflammatory bowel disease | Less bacterial diversity ↓ the number of Bacteroides and Firmicutes | decreasing the concentration of butyrate | Lucas López et al. (2017) |
Irritable bowel syndrome—diarrhea | ↑Enterobacteriaceae↓Faecalibacterium prausnitzii | not known | Dupont (2014) |
Constipation | ↑Firmicutes(Lachnospiraceae and Ruminococcaceae)↓Bacteroidetes (Prevotella) | increasing the production of butyrate | Zhu et al. (2014) |
Obesity | Changes in the ratio of Bacteroidetes/Firmicutes↓ the abundance Akkermansia muciniphila↑ the abundance Campylobacter, Shigella, Prevotella | decreasing the production of butyrate | Festi et al. (2014),Tremaroli & Bäckhed (2012) |
Diabetes T2 | ↓Bifidobacterium spp significant association of Parabacteroides with diabetic patients | not known | Wu et al. (2010) |
↓Firmicutes↑Bacteroidetes, Proteobacteria | it is possible to determine endotoxemia → oxidative stress → IL1, IL6, TNF α | Marlene (2013) | |
Diabetes T1 | ↓Lactobacillus, Bifidobacterium, Blautia coccoides–Eubacterium rectale, Prevotella | decreasing the production of butyrate decreasing the synthesis of mucin increasing the intestinal permeability | Murri et al. (2013) |
↓Clostidium clusters IV and XIV (species that produce butyrate) | decreasing the production of butyrate | De Goffau et al. (2014) | |
Dyslipidemia | ↓Lactobacillus | decreasing enzymatic deconjugation of bile acids → increasing the level of cholesterol | Kumar et al. (2012), Ramakrishna (2013) |
Nonalcoholic steatohepatitis | ↓Firmicutes↓Faecalibacterium and Anaerosporobacter (order Clostridiales)↑Parabacteroides and Allisonella (order Aeromonadales) | increase in luminal gut ethanol production metabolism of dietary choline release of lipopolysaccharides increasing small intestinal bacterial overgrowth increasing endotoxemia increasing lipopolysaccharide →↑ insulin resistance and ↑ TNF alpha | Compare et al. (2012), Wong et al. (2013) and Machado & Cortez-Pinto (2012) |
Acute coronary syndromes | not know | trimethylamine is formed by gut microbiota from nutrients which contain l-carnitine, choline, phosphatidylcholine followed by the formation of trimethylamine N-oxide (TMAO) by hepatic enzymes increasing the plasmatic level of TMAO–increasing the risk of myocardial infarction and stroke | Trøseid (2017) |
Autistic spectrum disorders | ↑Clostridium histolyticum (Clostridium clusters I and II)↑Bacteroidetes, Desulfovibrio↓Firmicutes | increasing the production of neurotoxins | Parracho et al. (2005), De Angelis et al. (2013) |
Allergy | ↑Lactobacillus, Enterococcus | increasing of allergic sensitization | Kirjavainen et al. (2002) |
low diversity of microbiota ↑Bacteroidales↓Clostridiales | not know | Hua et al. (2016) |
Dr. Rob Knight’s eleven point punch list of things that seem to be beneficial to the microbiome are:
- Eat lots of plants: 5 to 30 different varieties each week preferably. This finding is so profound that “American Gut” will soon change participant food journal requirements to “only ask for frequency on consumption of holistic food within the past month, instead of the three week food journal. This change is warranted since the long term diet, especially meat and fiber consumption, has been shown to have the largest effect on the microbiome.”
- Aging increases microbiome diversity: Microbiomes are more diverse at age 50 to 60 then populations in their twenties (see above slides).
- Having an IBD diagnosis means your microbiome is altered. NOTE: Many chronic and autoimmune diseases are also following suit.
- The time of year alters the microbiome with a more diverse microbiome being with sun and outdoor exposure.
- Antibiotics wipe the microbiome with some folks recovering relatively soon whereas others do not recover the pre-antibiotic microbiome even one year later.
- Males vs females: The sex for a given microbiome can now be accurately predicted.
- Sleep 8 hours for a more diverse microbiome. Less than 6 hours yields a less diverse microbiome.
- BMI but it only subtly affects the microbiome.
- Plants: eating 6 to 10 each week is good, but eating 30 plus different varieties is best. (See further discussion below.)
- Alcohol: one drink is helpful, more than one reduces diversity.
- Frequent exercisers have a more diverse microbiome and it is best if exercise is outdoors rather than indoors.
What’s up with plants and the microbiome?
Here is a great read where Dr. Knight and Jeff Leach talk about plants (and their fiber): Can We Eat Our Way To A Healthier Microbiome? It’s Complicated. In sum, “eating too little fiber could starve the bacteria we want around. “When we starve our bacteria they eat us,” Leach says. “They eat the mucus lining – the mucin in our large intestine.” Knight adds that when we do keep our bacteria well fed, they, in turn, give off nutrients that nourish the cells that line our guts. Fiber, Knight says, “is thought to be good for your gut health over all.” You can read the post, Fiber Additives Starve Gut Microbes. They Eat Mucus Lining for more on all that! Bottom line: Harness this information to positively nudge your microbiome towards health. Note too that everyone is uniquely different so the right diet depends a lot on the individual’s lifestyle AND that individual’s microbes. More tips from the article are:
- There are a lot of different ways to get fiber. Leach recommends getting it from vegetables. Eat a variety of veggies, and eat the whole thing, he recommends. “If you’re going to eat asparagus, eat the whole plant, not just the tips,” he says.
- Fiber was also central to Leach’s suggestion to Stein to eat more garlic and leek. Those vegetables contain high levels of a type of fiber called inulin, which feeds actinobacteria in our guts. In fact, inulin is considered a prebiotic, since it feeds the good bacteria, or probiotics, that live inside us.
- Garlic actually has antimicrobial properties, which paradoxically, could also be good thing for our microbiomes. One study shows that garlic hurts some of the bad bacteria in our guts while leaving the good guys intact. [Filocamo et al 2012]
- Eat fermented foods which contain probiotics along with foods that feed those probiotics. Fermented foods like kimchi, sauerkraut and yogurt might be surer sources of probiotics. Researchers are unclear about whether these have any lasting effect on the composition of our microbiome, but in some cases they do seem to help. “Epidemiologically there seems to be some evidence that eating fermented food is beneficial rather than harmful,” Knight says. But researchers are still trying to figure out why.
⇒ A key benefit of fiber beyond regularity, is that when the microbiome ferments it, short chain fatty acids (SCFAs) are produced.
This study, from Nutrition & Diabetes, summarizes SCFA nicely: “Colonic fermentation is a complex process that occurs through the interactions of many microbial species and involves the anaerobic breakdown of dietary fibre, protein and peptides.1, 2, 3 The principal end products of colonic fermentation are the short chain fatty acids (SCFAs) acetate, propionate and butyrate, the gases hydrogen, carbon dioxide and methane4, 5, 6 and energy, which is used by the microbiota for growth and maintenance of cellular functions.7 Small amounts of branched chain fatty acids (iso-butyrate, valerate and iso-valerate) are also formed from protein and amino acid degradation. The amount and type of dietary fibre are among the major determinants of gut microbial composition and SCFA production patterns.8 In humans, the SCFA produced account for 5–10% of total dietary energy.9 ) [Fernandes et al 2014]