Blog: Clinical Trials-Diet/Environment/Disease, Blog: Microbiome & Newborn, Pillar: Toxins

1st Study: Low Dose BPA Perinatal Exposure & Food Intolerance

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There has been a lot of recent discussion about BPA, especially as it affects infants.  Now we see for the first time, that low dose BPA perinatal exposure is associated with food intolerance, specifically the egg white protein, at least for rats.  Remember the alternative, BPS, is even less studied and some say it is worse than BPA.

This January 2014 study, showed that BPA is in both breast milk and newborn and infant urines regardless if breastfed or formula fed. “RESULTS:  Total BPA was detected in 93 % of urine samples in this healthy infant population aged 3-15 months who were without known environmental exposure to BPA . Similarly, 75 % of the mothers’ breast milk samples had detectable concentrations of total BPA.”

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Blog: Microbiome, Blog: Microbiome & Fiber, CME_Microbiome, MICROBIOME WELLNESS PROGRAM, Pillar: Exercise, Pillar: Sleep, Wellness Vendor (Microbiome focus), Whole Food, Worthwhile Resources - Podcasts, Books...

Optimal Microbiome Diet From American Gut Data

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SUMMARY (updated Aug 2018):  Dr. Rob Knight’s talk, Saturday, October 18, 2014, listed eleven factors that optimize the gut microbiome based on the American Gut Data cautioning all is preliminary.  These are listed below along with an interesting article titled:  “Can We Eat Our Way To A Healthier Microbiome? It’s Complicated,” in which Dr. Knight and Jeff Leach (founders of crowd sourcing project “American Gut”) discuss the microbiome diet.  A KEY finding was that the more vegs consumed (30 different each week is BEST), the more diverse the microbiome, and that is thought to be associated with health and improved immune status since MANY chronic diseases (see the below Table) have changes in microbiome diversity AND composition, [Cantinean et al 2018].  A 2018 update on the American Gut data just published, [McDonald et al 2018], and it still says to eat 30 different vegs each week! This post also provides insight into what the microbiome experts are saying about translation of microbiome research into clinical practice.  And last, my synopsis of Dr. Knight’s talk is provided (see below the light bulb) along with my listing of fav microbiome researcher labs whose work is discussed in this post! Use them and PUBMED for your own disease prevention or mitigation research. Always. Stick with the evidence for answers as this blog does.

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Blog: Microbiome, Worthwhile Resources - Podcasts, Books...

Catch Today, 1-4pm, Dr. Rob Knight Microbiome Talk

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UPDATE:  You’ve missed the talk but can definitely catch the synopsis at “Optimal Microbiome Diet From American Gut Data.“  Dr. Knight gave an “Eleven Point” punch list of factors that hugely affect the microbiome.  Totally intriguing and insightful data is now being generated!

Definitely FOOD FOR THOUGHT!

Hey! I am copying yesterday’s Facebook post that shouted out today’s unique opportunity for all to hear FREE Dr. Rob Knight (bio is at end of post) speak on the human microbiome and diet implications.  Sorry for the late notice but I received the invitation email only yesterday.

Anyway, it is a great opportunity to hear one of the most leading edge microbiome researchers that I know.  You can catch it live free (this is a continuing education course) if you live near University of Colorado Boulder, and if not, you can catch a live stream online,  http://conted.colorado.edu/courses/introduction-to-your-human-microbiome/#, and possibly throughout the weekend.  I encourage all to take advantage of hearing Rob… he is amazing! If the links don’t work.. email me and I’ll forward the letter. Have a great weekend!

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Whole Food, Worthwhile Resources - Podcasts, Books...

Jaminet & Bailor on “Perfect Health Diet”

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There’s a fellow health researcher that I respect;  his name is Paul Jaminet, creator and blogger over at “The Perfect Health Diet” site.  Jaminet has no hidden agenda.   He had a health problem, and used his science background to research.  What he found is nearly in line with everything that I speak of, which is SCD/GAPS/PALEO/ MEDITERANEAN… and so many other wonderful healing diets:

“When you’re doing things the right way, usually you see results very quickly, so it’s well worth taking a little bit of time to read and think about these things and to do a personal experiment and see how they affect you.“

“When you’re doing it correctly, you should see results and you should feel good.”

To me, Paul is the epitome of: “Here’s what the science and here’s what the research shows, and I hope it will help you.”   Paul has absolutely, no hidden agenda.

I’d be remiss to not mention Paul’s wife, Shou-Ching Shih, a coauthor of the book “Perfect Health Diet.”  This couple is beyond brains:  Paul was an astrophysicist at the Harvard-Smithsonian Center for Astrophysics, became a software entrepreneur during the Internet boom, and now provides strategic advice to entrepreneurial companies while pursuing research in economics.  Shou-Ching is a molecular biologist and cancer researcher at Beth Israel Deaconess Medical Center and Harvard Medical School, and Director of BIDMC’s Multi-Gene Transcriptional Profiling Core. Nuff said.

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Blog: Clinical Trials-Diet/Environment/Disease, Blog: Microbiome & Newborn

Delivery & BreastFeed Studies & Newborn Microbiome Manipulation

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Summary: Newborn microbiome differs by mode of delivery and feeding.  Newborn C-section microbiome:  Swabbing C-section babies partially restores the newborn microbiome.
First, a quick refresher of “How we acquire our gut microbiome.“

Our gut microbiome is acquired at birth, though this is by no means a simple answer.  The post “Newborn Gut Microbiome Begins at Birth”  details many differences between the newborn gut microbiome  due to mode of delivery (vaginal versus C-Section) as well as feeding (breast-fed versus formula-fed).  The figure below extends this and shows the recent findings that the developing microbiome is shaped not only by delivery and feeding mode, but that antibiotics, probiotics, and environmental exposures also interact and develops the newborn’s microbiome and resultant immune system.

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Blog: Microbiome, Pillar: Toxins, Whole Food

MICROBIOME, WHAT DISRUPTS IT?

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SUMMARY:   We now understand that disease management requires understanding of:  what is the microbiome, what disrupts it, and what positively affects it.  This post discusses: What is the microbiome, implications of reduced diversity, long term therapeutic diet impact on microbiome, the IBD annual meeting is starting to consider the microbiome, some anecdotal microbiome stories, and why you want microbiome balance & diversity.
FIRST A RECAP (if you already are versed on this information, skip right on down to the Microbiome, What Disrupts It and How to Optimize sections of this post):  
Microbiome_WhatAndDisrupt
biomeonboardawareness.com
What is the Microbiome?

It is estimated that the human microbiota contains as many as 1014 bacterial cells, a number that is 10 times greater than the number of human cells present in our bodies.  It is more accurate to say we are hosts of our microbiome rather then that we are human.  The human body is permanently colonized by microbial organisms on virtually every surface that is exposed to the external environment and each such surface has a different microbiome:  skin, mouth, genitalia, genitourinary, respiratory tracts, and the largest colonize, the gut (aka gastrointestinal).  The trillions of organisms live on and in us are collectively called the microbiome: a balanced ecosystem. –“Gut Microbiota in Health and Disease,”

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Blog: Autism, Blog: Clinical Trials-Diet/Environment/Disease, Blog: IBD, Blog: Microbiome, Blog: Microbiome & Butyrate, Whole Food

Food Managing IBD & AUTISM: The Studies

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SUMMARY:  Anytime food choices turns around chronic disease with studies that prove such, that should be an eye opener!  Implementing principles of such diets should be considered for anyone wanting to prevent or manage chronic disease.  This post presents studies for Food Managing IBD & AUTISM, where dietary protocols achieved remission and management (with reduction, if not elimination of medication) for autoimmune IBD , or positively altered the course of autism.

HOW?  Diet can optimize (or modulate) the gut microbiome which is the source of 80 – 85 percent of our immunity:  

The “1st International Symposium on the Microbiome in Health and Disease with a Special Focus on Autism,” July 2014: “the microbiome refers to the constellation of enteric bacteria that create an organ system that makes up 80% of our immune system...“

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Blog: Clinical Trials-Diet/Environment/Disease, Blog: Diabetes, Blog: Microbiome

Testing if calories trigger hormones that regulate fat cell behavior

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Summary:  NUSI is now testing if calories trigger hormones that regulate fat cell behavior.  This will help answer the question of  which camp we should we be in, namely:  the sugar is  bad/saturated fat is the good camp versus the whole grain/low fat is the good camp. 

Enter NUSI →   Seems bad science got us into the mess and state of confusion and ignorance.  So Gary Tuabes has aligned with Dr. Peter Attia, MD to do “good science“ and answer the age old question:  Do we get fat because we eat too much and especially too much fat OR is it the food we eat, especially the increased consumption of table sugar and other refined carbohydrates the likely explanation for our current chronic disease epidemic including obesity?  There’s a real difference there, honest!

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Blog: IBD, Blog: Microbiome, Blog: Microbiome & Butyrate, Whole Food

Microbiome DIET Mechanisms Prevent or Manage Disease (Focus: SCD & IBD)

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Summary: Watch the short video to learn why most of your immunity resides in your gut. Then read about predictive autoimmunity in preventative medicine; the role of gut permeability, and disease, as well as how autoimmunity may contribute to cardiovascular disease risk, and the role of antibodies in unexplained miscarriages. The pearl is have a healthy gut which is your first-line immune defense. To that end, learn what the microbiome diet mechanisms are that prevent or manage disease with a focus on SCD and IBD.

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Blog: Diabetes, Blog: Microbiome, Blog: Thyroid, Pillar: Toxins

Antibacterials and microbiome: SHOW SAFETY or REMOVE per FDA

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Antibacterials and microbiome — real cause for concern:

FINALLY, the FDA has given soap manufacturers one year to demonstrate that antibacterial additives are safe or to take them out of the products altogether.  This is great considering it has been found in the urine of 3/4 of Americans, and it is detected in 97% of breast-milk tested.  The FDA issued the proposed rule on Dec. 16, 2013 requiring manufacturers to provide more “substantial data” to demonstrate the safety and effectiveness of antibacterial soaps. The proposed rule is limited however and covers only those consumer antibacterial soaps and body washes that are used with water. 

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