Category Archives: Blog: Leaky Gut

Move over gluten, ATI wrecks guts too.

SUMMARY.  This post looks at other ways beyond Celiac and NCGS, that wheat can affect EVERYONE and includes new groundbreaking research being presented in Vienna.  The bottom line:  Move over gluten, ATI wrecks guts too, and… we have a new picture of what the inflamed gut looks like!  ATIs, or amylase-trypsin inhibitors, are non-gluten proteins in wheat.  ATIs activate specific types of immune cells [toll-like receptor 4] in the gut and other tissues.   ATIs can trigger gut immune reactions that can spread to other tissues in the body.  How bad can this get?  “ATIs can lead to the development of inflammation in tissues beyond the gut, including the lymph nodes, kidneys, spleen and brain.   ATIs can worsen the symptoms of pre-existing inflammatory based conditions like RA, MS, asthma, lupus, IBD, and non-alcoholic fatty liver disease…”   The final big hit:  “ATIs may contribute to the development of non-coeliac gluten sensitivity (NCGS).”  No wonder so many feel better ditching wheat since you knock out both gluten and ATIs AND decrease inflammation not just in the gut, but systemically!  For an example, IBD and neurological  association to ATI is discussed below!  What about the  non-gluten containing staples you may be consuming?  Those displayed no or little of the toll like receptor 4 stimulating activity whereas ATIs displayed much! 

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Alzheimer’s Diet, Microbiome, & Bio-marker Predictors

SUMMARY:  Learn the latest on Alzheimer’s Diet, Microbiome, & Bio-marker Predictors.  Such is welcome news as the latest Alzheimer’s Facts & Figures show that over 5 million Americans are living with Alzheimer’s, including an estimated 200,000 under the age of 65.  

By 2050, the number of people age 65 and older with Alzheimer’s disease may nearly triple, from 5 million to as many as 16 million.  Truly, Alzheimer’s is one of the diseases most feared in my talks; it is the sixth-leading cause of death in the United States.   The estimate is that by age 64, one in 8 will have Alzheimer’s.  That rate doubles every 5 years.  So by age 70, one in 4 will have Alzheimer’s.  And by age 75, one in 2 will have Alzheimer’s.  These stats are from a 2013  interview of Dr. Thomas Wisniewski, @ time 25:30: “Brains – The Latest Research 07/01/2013 – 08:04” (NYU Langone Medical Center Audiocast, SirusXM Dr. Radio programming), who’s lab, Dr. Thomas Wisniewski’s Lab, is one of the leading Alzheimer research labs.

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