Tag Archives: biome

Crowd Sourcing DNA Sequencing for Autism

“Lots of things are mysteries. But that doesn’t mean there isn’t an answer to them. It’s just that scientists haven’t found the answer yet.   – Christopher John Francis Boone, “If you put 10,000 people’s genomes in the cloud, could you demystify autism?”

It’s happening!   Cancer and autism is leading the way “Medicine will soon rely on a kind of global Internet-of-DNA which doctors will be able to search on Goggle’s cloud platform. “Our bird’s eye view is that if I were to get lung cancer in the future, doctors are going to sequence my genome and my tumor’s genome, and then query them against a database of 50 million other genomes. The result will be ‘Hey, here’s the drug that will work best for you.’ ”“

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Alzheimer’s Diet, Microbiome, & Bio-marker Predictors

SUMMARY:  Learn the latest on Alzheimer’s Diet, Microbiome, & Bio-marker Predictors.  Such is welcome news as the latest Alzheimer’s Facts & Figures show that over 5 million Americans are living with Alzheimer’s, including an estimated 200,000 under the age of 65.  

By 2050, the number of people age 65 and older with Alzheimer’s disease may nearly triple, from 5 million to as many as 16 million.  Truly, Alzheimer’s is one of the diseases most feared in my talks; it is the sixth-leading cause of death in the United States.   The estimate is that by age 64, one in 8 will have Alzheimer’s.  That rate doubles every 5 years.  So by age 70, one in 4 will have Alzheimer’s.  And by age 75, one in 2 will have Alzheimer’s.  These stats are from a 2013  interview of Dr. Thomas Wisniewski, @ time 25:30: “Brains – The Latest Research 07/01/2013 – 08:04” (NYU Langone Medical Center Audiocast, SirusXM Dr. Radio programming), who’s lab, Dr. Thomas Wisniewski’s Lab, is one of the leading Alzheimer research labs.

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Autism Microbiome Study: 2 Studies Seek Participants

The 1st major funded Autism Microbiome Study:

“Autism Speaks Invests $2.3 Million in Research on Autism Gut-Brain Connection, which makes these studies the first major funded GI initiative that investigates microbiome, biological stress and  bowel  disorder treatment in children with autism.  

Clinical trials will span 3 years and are now filling if you are interested.  Please share this information on Facebook, Twitter, Pinterest… so that others can participate.  While this research might be a decade or so behind what parents know, it’s two decades ahead of our GP and many autism treatment facilities, so it’s needed, it’s important, and I’m very grateful to hear about it.

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By 2030 adult young colon cancer diagnoses doubles

SUMMARY: Learn here that adult young colon cancer diagnoses doubles by 2030.

The number of young adults (aged 20 to 34, and 35 to 49 years) with newly diagnosed colorectal cancer is anticipated to nearly double by 2030.

Worth repeating:  By 2030 adult young colon cancer diagnoses doubles

For ages 20 to 34 years, colon cancer increase is 90.0% and rectal cancer increase is 124.2% by the year 2030.

For ages 35 to 49 years, colon cancer increase is 27.7% and rectal cancer increase is 46.0% by the year 2030.

For patients under age 34, the increase is across all stages of disease: localized (confined to the colon or rectum), regional (contiguous and adjacent organ spread, such as to the lymph nodes, kidney and pelvic wall) and distant (referring to remote metastases).

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Optimal Microbiome Diet From American Gut Data

SUMMARY (updated Aug 2018):  Dr. Rob Knight’s talk, Saturday, October 18, 2014, listed eleven factors that optimize the gut microbiome based on the American Gut Data cautioning all is preliminary.  These are listed below along with an interesting article titled:  “Can We Eat Our Way To A Healthier Microbiome? It’s Complicated,” in which Dr. Knight and Jeff Leach (founders of crowd sourcing project “American Gut”) discuss the microbiome diet.  A KEY finding was that the more vegs consumed (30 different each week is BEST), the more diverse the microbiome, and that is thought to be associated with health and improved immune status since MANY chronic diseases (see the below Table) have changes in microbiome diversity AND composition[Cantinean et al 2018].  A 2018 update on the American Gut data just published, [McDonald et al 2018], and it still says to eat 30 different vegs each week! This post also provides insight into what the microbiome experts are saying about translation of microbiome research into clinical practice.  And last, my synopsis of Dr. Knight’s talk is provided (see below the light bulb) along with my listing of fav microbiome researcher labs whose work is discussed in this post! Use them and PUBMED for your own disease prevention or mitigation research. Always. Stick with the evidence for answers as this blog does.

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Catch Today, 1-4pm, Dr. Rob Knight Microbiome Talk

UPDATE:  You’ve missed the talk but can definitely catch the synopsis at “Optimal Microbiome Diet From American Gut Data.  Dr. Knight gave an “Eleven Point” punch list of factors that hugely affect the microbiome.  Totally intriguing and insightful data is now being generated!

Definitely FOOD FOR THOUGHT!

Hey! I am copying yesterday’s Facebook post that shouted out today’s unique opportunity for all to hear FREE Dr. Rob Knight (bio is at end of post) speak on the human microbiome and diet implications.  Sorry for the late notice but I received the invitation email only yesterday.

Anyway, it is a great opportunity to hear one of the most leading edge microbiome researchers that I know.  You can catch it live free (this is a continuing education course) if you live near University of Colorado Boulder, and if not, you can catch a live stream online,  http://conted.colorado.edu/courses/introduction-to-your-human-microbiome/#, and possibly throughout the weekend.  I encourage all to take advantage of hearing Rob… he is amazing! If the links don’t work.. email me and I’ll forward the letter. Have a great weekend!

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MICROBIOME, WHAT DISRUPTS IT?

SUMMARY:   We now understand that disease management requires understanding of:  what is the microbiome, what disrupts it, and what positively affects it.  This post discusses: What is the microbiome, implications of reduced diversity, long term therapeutic diet impact on microbiome, the IBD annual meeting is starting to consider the microbiome, some anecdotal microbiome stories, and why you want microbiome balance & diversity.
FIRST A RECAP (if you already are versed on this information, skip right on down to the Microbiome, What Disrupts It and How to Optimize sections of this post):  
Microbiome_WhatAndDisrupt
biomeonboardawareness.com
What is the Microbiome?

It is estimated that the human microbiota contains as many as 1014 bacterial cells, a number that is 10 times greater than the number of human cells present in our bodies.  It is more accurate to say we are hosts of our microbiome rather then that we are human.  The human body is permanently colonized by microbial organisms on virtually every surface that is exposed to the external environment and each such surface has a different microbiome:  skin, mouth, genitalia, genitourinary, respiratory tracts, and the largest colonize, the gut (aka gastrointestinal).  The trillions of organisms live on and in us are collectively called the microbiome: a balanced ecosystem. “Gut Microbiota in Health and Disease,”

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Food Managing IBD & AUTISM: The Studies

SUMMARY:  Anytime food choices turns around chronic disease with studies that prove such, that should be an eye opener!  Implementing principles of such diets should be considered for anyone wanting to prevent or manage chronic disease.  This post presents studies for Food Managing IBD & AUTISM, where dietary protocols achieved remission and management (with reduction, if not elimination of medication) for autoimmune IBD , or positively altered the course of autism.

HOW?  Diet can optimize (or modulate) the gut microbiome which is the source of 80 – 85 percent of our immunity:  

The “1st International Symposium on the Microbiome in Health and Disease with a Special Focus on Autism,” July 2014: “the microbiome refers to the constellation of enteric bacteria that create an organ system that makes up 80% of our immune system...

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Testing if calories trigger hormones that regulate fat cell behavior

Summary:  NUSI is now testing if calories trigger hormones that regulate fat cell behavior.  This will help answer the question of  which camp we should we be in, namely:  the sugar is  bad/saturated fat is the good camp versus the whole grain/low fat is the good camp. 

Enter NUSI →   Seems bad science got us into the mess and state of confusion and ignorance.  So Gary Tuabes has aligned with Dr. Peter Attia, MD to do good science and answer the age old question:  Do we get fat because we eat too much and especially too much fat OR is it the food we eat, especially the increased consumption of table sugar and other refined carbohydrates the likely explanation for our current chronic disease epidemic including obesity?  There’s a real difference there, honest!

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Microbiome DIET Mechanisms Prevent or Manage Disease (Focus: SCD & IBD)

Summary: Watch the short video to learn why most of your immunity resides in your gut. Then read about predictive autoimmunity in preventative medicine; the role of gut permeability, and disease, as well as how autoimmunity may contribute to cardiovascular disease risk, and the role of antibodies in unexplained miscarriages. The pearl is have a healthy gut which is your first-line immune defense. To that end, learn what the microbiome diet mechanisms are that prevent or manage disease with a focus on SCD and IBD.

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