FEED YOUR MICROBIOME TO MANAGE AUTISM

Microbiome and autism…  Feeding your gut microbiome could exacerbate, or modulate, autism symptoms.  That understanding is incredibly empowering to those that must manage autism!

It is now undisputed that the gut microbiome differs in autism compared to healthy controls:

“At the annual meeting of the American Society for Microbiology held in May in Boston, researchers at Arizona State University reported the results of an experiment in which they measured the levels of various microbial by-products in the feces of children with autism and compared them with those found in healthy children. The levels of 50 of these substances, they found, significantly differed between the two groups. And in a 2013 study published in PLOS ONE, Italian researchers reported that, compared with healthy kids, those with autism had altered levels of several intestinal bacterial species, including fewer Bifidobacterium, a group known to promote good intestinal health.”  “Gut Bacteria May Play a Role in Autism”, Scientific American, Aug 2014.  

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SCD Managing IBD, RUSH Medical Center

SCD managing IBD is nothing new.   RUSH University Medical Center, Chicago is one facility that extensively studies SCD and IBD.

I am now aware of two studies RUSH  intends to publish by the end of 2014. The first is to identify “characteristics common for those for whom SCD works to manage IBD.”  My contact was not allowed to share at this time what the second study’s content will be.

RUSH is not alone however in the study of SCD and IBD; I have written extensively on the science of SCD success here:

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Digestion: You & Your Microbiome Eats

You eat to feed your microbiome,  which in turn, feeds you, or not.
YOU CAN BE WELL FED… BUT MALNOURISHED!

You are NOT what you eat which is contrary to what we hear time and again.

  • Rather, you are what you feed your microbiome.  
  • You are what you digest.
  • You are what you absorb. 

We will discuss lots of practical digestion strategies beginning at the brain and ending at… yep, the commode.

Arguably, poor digestion is the leading cause of disease in the US.   A dsyfunctional gut:
  1. Impairs absorption of vitamins and minerals,
  2. Increases the risk of infections in the gut as well as systemically since immunity is reduced (80 to 85% of our immunity is in the gut),
  3. Increases the risk of abnormal bacterial overgrowth as well as yeast overgrowth in the gut since a pathogenic microbiota can flourish at the expense of beneficial microbiota,
  4. Down regulates our immune system since the gut is unable to perform it’s role of digestion of vitamins and minerals, manufacture of vitamins and antibiotics, and maintenance  of a homeostasis balanced microbiome ecosystem,
  5. Conditions that can result from poor digestion include:
    • SIBO
    • FODMAPS intolerance
    • Fructose malabsorption
    • IBS
    • Gluten sensitivity
    • Other food sensitivities
    • Increased intestinal permeability 
    • Autoimmunity
    • Systemic inflammation:  In addition to gliaden crossing the gut wall, LPS (end-products of certain microbiota strains) crosses the gut wall).  LPS can then cross the blood/brain barrier and impact brain health.  LPS is in fact used in research to induce inflammation in animals as noted in this Medical News Today article, “Newly created turmeric-based formulation releases anti-inflammatory power throughout body “: The researchers injected mice with lipopolysaccharide, a bacteria cell wall extract that stimulates an immune reaction in animals. Curcumin can target many molecules, but the research team zeroed in on NF-kB, a protein that is known to play an important role in the immune response.”  
  6. An antibiotic impacted gut can decrease microbiome  diversity  which is associated with reduced immune system functioning.

To begin, understand enzymes and deficiencies which are a root cause of microbiome disruption having disease consequences by reading the post: “Digestive Enzymes & Disease w/Focus On Autism”.

And for more on microbiome impact from eating nutrient dense, anti-inflammatory whole foods, check out:

“Some of My Best Friends Are Germs”, NY Times article, Michael Pollan, May 2013.

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Microbiome Changes from Diet & Enviro Affect Health_Alm

Summary:   Eric Alm’s MIT lab gene sequencing shows microbiome changes from diet & environment (antibiotics and international travel.) Changes to microbiome due to antibiotic was permanent.

I am the ninth viewer of this Microbiome Manipulation via Diet and Environment (YouTube), Eric Alm, PhD, MIT.  It doesn’t get much more current than that!  The study Dr. Alm discusses (daily stool sequencing for one year for several participants) can be read at Host lifestyle affects human microbiota on daily timescales

Dr. Eric Alm is one of my favorite researchers; our paths first crossed with Eric Alm: A year in the life of my gut microbiome (2012 GET Conference) (YouTube) which is re-discussed in the second section of his most recently published YouTube.  The 2012 GET Conference provides more insight though, if desired, into the second Pearl listed below.

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WHAT WHOLE FOOD LOOKS LIKE, YES!

SUMMARY: Learn what whole food looks like. Such are anti-inflammatory and nutrient dense; the key to reducing, managing and even reversing chronic disease.

Seems in today’s lifestyle, what whole food looks like is confusing.  Is it the steaming hot prepared buffet luring you with it’s smells and convenience such even appearing at Whole Foods grocery stores?

A check of ingredients will show if it is pure, clean, delicious, and properly prepared real nourishing whole food.  Such is anti-inflammatory and nutrient dense. I am excited that you are learning this concept!

Adhering to an anti-inflammatory diet is the answer to reducing, managing, and even reversing chronic disease. 

Through diet we  increase anti-inflammatory Omega-3 fatty acids, decrease inflammatory (Omega-6 fatty acids, and food intolerances), and increase fruits and vegetables to increase antioxidants, vitamins and minerals. High quality meat, grains, and diary have a place in a nutrient dense diet but learning food quality and individual tolerance is critical for optimizing health.  

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MICROBIOME RULES; WHAT IS MICROBIOME?

SUMMARY:  Your gut microbiome allows you to live your life with health, wellness, and vitality, or illness and disease.  Without a doubt, the MICROBIOME RULES; WHAT IS MICROBIOME?

If you haven’t already done so, you should read the post, “Diet and other things Determines Our Microbiome” to be certain you are up to date not only with what this dynamic virtual organ is, but also are cognizant of the many factors that affect the microbiome.  
We can modulate this microbiome; the science is exploding daily with research that is unveiling the vast impact the gut microbiome has on all of our inner workings.
FOOD ALTERS THE MICROBIOME, with a focus here on celiac and autism, although the insight applies to all autoimmunes and chronic disease.

The post “Food Managing Autism and IBD: The Studies,” details the studies (and includes current ongoing clinical trials) showing dietary intervention (that heals the gut) can result in IBD remission or management of autism.  Such occurs through optimization of the microbiome since the food we feed the microbiome, determines the gut’s community of microbiota, whose role is to affect immunity, health, wellness, and vitality.  Thus, anyone looking to improve health needs to look first at optimizing the gut microbiome.

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A FEW INDEX CARD RECIPES FOR WHOLE FOODS

Summary:  This post give A FEW INDEX CARD RECIPES FOR WHOLE FOODS. Snip and save!  I get it.  You don’t know how to cook or bake, but you know you have to figure this out.  Or maybe you are a genius in the kitchen, but…  Whoever heard of coconut flour, rancid industrial seed oils, grass-fed or pastured animals and animal by-products, or of soaking, sprouting, and dehydrating grains, nuts, seeds, and legumes for proper preparation to neutralize the inflammatory compounds inherent within these foods that is so disease promoting?  And… that listing is just a few incidentals of Whole Food preparation!  Don’t despair.  Most “Whole Food” foodies did not know how to cook using such ingredients and techniques at the beginning either as ALL of us were unfamiliar with such!  To help get you started, here are some index cards, but there’s more posted on the website (see below for how to locate those), and on my  Pinterest!

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DIET & OTHER THINGS: WHAT DETERMINES MICROBIOME?

Summary:  WHAT DETERMINES MICROBIOME?  Learn that we truly are what we eat, inhale, and absorb since that is what feeds our microbiome.   70% of the microbiome is very stable and supports basic life function, but 30% is very variable and host manipulable. A 30% change is huge because for the microbiome, 30% of the 39 trillion bacterial cells comprising the microbiome results in nearly 11.7 trillion organisms that can be modulated through diet and lifestyle nudging towards an anti-inflammatory state.  These changes increase immunity; 80% of our immunity comes from our gut microbiome.

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CANCER MICROBIOME IS MESSED UP?

SUMMARY:  CANCER MICROBIOME.  Be it linked to the gut microbiome or specific tissue,… It was just a matter of time until researchers linked cancer to the microbiome.

Cancer Microbiome

“These studies demonstrate that microbiota can increase or decrease cancer susceptibility and progression by diverse mechanisms such as by modulating inflammation, influencing the genomic stability of host cells and producing metabolites that function as histone deacetylase inhibitors to epigenetically regulate host gene expression. One might consider microbiota as tractable environmental factors because they are highly quantifiable and relatively stable within an individual compared with our exposures to external agents. At the same time, however, diet can modulate the composition of microbial communities within our gut, and this supports the idea that probiotics and prebiotics can be effective chemoprevention strategies. The trajectory of where the current work is headed suggests that microbiota will continue to provide insight into the basic mechanisms of carcinogenesis and that microbiota will also become targets for therapeutic intervention.” – Emerging roles of the microbiome in cancer, Carcinogenesis. 2013 Dec 3. [Epub ahead of print]

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