Category Archives: Blog: IBD

IBS, Microbiome, Fodmaps, Probiotics

SUMMARY:   Bottom Line of this post: You want OFF the IBS diseasepan!  WHY? Because — putting aside pain, bowel issues, and bloat — IBS can alter the brain size and function in the emotion and sensory processing areas when having it a long time along with early life stressors [Labus et al., 2017], it is associated with a lot of diseases, and there are a lot of surgeries performed inappropriately because of misdiagnosis or poor manangement of IBS!  DISEASES associated with IBS — it is not comprehensive: Type 2 Diabetes, metabolic syndrome, fibromyalgia, chronic fatigue syndrome, IBD, CFS/ME, autism, anxiety, depression, MS, and Parkinson’s.  Inappropriate SURGERIES occurring due to IBS  misdiagnosis —  appendectomy, cholecystectomy, ovarian, and hysterectomy.  See below for All of those links. There are lots of ways to get off the IBS diseasespan!  Learn in this post that it is YOUR choice:  IBS, Microbiome, Fodmaps, Probiotics, Mindfulness-based stress reduction, Cognitive behavioral therapy works… or targeted drugs!  Or not drugs — the efficacy of that current US standard of care:  “The physician should also emphasize the chronic nature of this syndrome [IBS] because nearly 75% of patients continue to have a diagnosis of IBS 5 years later.13  [Occhipinti et al., 2012].   Many different drugs have been suggested for IBS treatment, but their real benefits are very debatable.”  [Bellini et al., 2014].   Don’t be surprised.  In 2012, the FDA changed the endpoints of those drug studies to stop being only one endpoint because of how multi factorial IBS symptomolgy is, and the Bristol Stool Chart — defining what is a ‘normal BM’ (which you’ll learn in this post) — despite being around since 1997, is only now being validated, 2016!  Contrast all this to the UK British Dietetic Association guidelines for IBS — low FODMAP diet is the second-line intervention [Catassi et al., 2017]  [McKenzie et al, 2016]   [UK evidence-based practice guidelines for dietetic management of IBS in adults 2012 PDF]) as it helps about seventy-six percent of IBS patients  [Magge et al., 2012]  [Bohn et al., 2015]   [Staudacher et al., 2011] and yet, it has come under attack with the current US standard of care still NOT recognizing the FODMAP diet (see this post).  A rebuttal to all the rift recently published in 2017, authored by Monash University ressearchers, the creators of the FODMAP diet.  See  [Hill et al., 2017]  To piggyback the diet fix, studies continue to find that probiotics might be something to think about for some cases of IBS — see  [Whiteley, 2016].  Wondering about IBS and what early life stressors might mean?  That group had more history of early life trauma (general trauma (31 items), physical (9 items), emotional (7 items), and sexual abuse (15 items)) AND they had longer duration of IBS symptoms.  [Labus et al., 2017]  While we can’t change our early life stressors, there are lots of ways to tackle IBS using diet, probiotics, mindfulness-based stress reduction, cognitive behavioral therapy and targeted drugs — according to the Monash rebuttal [Labus et al., 2017].  Now you know!  Protect brain size and function, avoid potentially needless surgery and improve your disease status by fixing IBS; LISTEN to your gut!  Unbelievable… check out the global prevalence of IBS:

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Concise Summary of SCD Studies

SUMMARY:  Here is the Concise Summary of Specific Carbohydrate Diet, or SCD Studies with a focus on SCD for dietary treatment for Inflammatory Bowel Disease (IBD).  Actually though, SCD is used for many conditions, not just IBD.  This post focuses on the boatload of studies evaluating SCD for IBD because that is where most of the SCD research is happening.  The findings support that once gut irritating foods are removed, the immune system changes because the gut microbiome changes. That should be true for whatever condition SCD is used for.  Take this Round-table of SCD studies to your doctor and ask for support especially if for IBD.  They should liaison with those already integrating the SCD into IBD dietary therapeutics.  SCD helps IBD with or without medications and can be used to induce remission for many with and without medications.  Always, the goal of treatment is IBD remission, not necessarily medication-free.  Half of the 417 patients surveyed [Suskind et al., 2016] use the SCD to induce remission; the other half use it adjunct to medications because of medication failure.  Think how many guts could be saved!  Dr. David Suskind (leading light GI at Seattle Children’s  Hospital integrating SCD into IBD clinical  dietary therapeutics) explains [Suskind Dietary Treatment  YouTube, 2016] that some use SCD alone if with mild to moderate symptoms at diagnosis.  Others use SCD along with medications and then once in remission, it may be possible to wean off medications.  Consider giving some of the SCD tenets (especially the emulsifier elimination) a try regardless of your disease, or for aggressive preventative health.  Diet that removes gut irritants is that powerful because it changes up the microbiome where over 70% of immunity resides!  What do you have to lose????  

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Defy Autoimmune Psoriasis: Green Tea, Black Tea, Lemon Juice Antioxidant

SUMMARY:  Plenty of studies find anti-inflammatory effects of dietary antioxidants such as green tea for chronic disease.  Even in IBD patients, who have a very messed up microbiome (a finding of the American Gut data), the  benefits of antioxidant therapy is well documented (see below studies).  Read here about a simple EASY N=1 hack for one IBD patient that shut down a mild psoriasis skin flare that began two years ago.  They flared psoriasis, but not the autoimmune IBD, eating strict healing diet Specific Carbohydrate Diet (SCD) probably due to a gluten/sugar airborne exposure.  The hack that worked for stopping psoriasis: Green Tea, Black Tea with Lemon Juice antioxidant blend!  I share their recipe here!   It is simple enough that you may want to add it to your immune calming anti-inflammatory arsenal too!  Make sure to see below for why it is important to NOT drink Green Tea for antioxidant benefit along with Iron.  

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Microbiome, Emulsifiers, IBD & Metabolic Syndrome

SUMMARY: Don’t be duped into believing diet has nothing to do with your disease, or in preventing disease.  When the researchers themselves rethink and change up their own diet to eliminate the ubiquitous food additive emulsifiers because their research is finding serious adverse impact on the gut lining, I want everyone to rethink their emulsifier intake too, for your gut’s health.  Meet here, Dr. Andrew Gewirtz  and learn about his important work on Microbiome, Emulsifiers, and their association with IBD and Metabolic Syndrome (defined by NIH as having three or more of these factors or you take drugs to control them:  High triglyceride level, reduced high-density lipoprotein (HDL) cholesterol, increased blood pressure, elevated fasting blood sugar, & large waist circumference.  How concerned should you be about chowing down emulsifiers?  Their connection to gut inflammation and microbiome skew at the mucosal level caused Dr. Gewirtz to eliminate such from his and his family’s diet.  One tenet of the healing diets — eliminate processed foods — results in the elimination of emulsifiers. Perhaps it is time to reconsider your emulsifier intake too.

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Finally, an IBD microbiome drug goes to clinical trial

Summary:  Seres Therapeutics began its Phase 1b placebo controlled clinical trial on Dec 14, 2015, for SER-287, which is the first drug aimed at the microbiome for a non-infectious, chronic condition, ulcerative colitis (UC).  This is the first IBD microbiome drug that actually targets the constituents of the microbiome. This approach treats chronic disease without suppressing  the body’s immune response. Instead, specific strains of bacteria are introduced that re-balance the billions of different types of bacteria that are in the digestive tract, which then increases immunity and manages the disease.  Instead of being immunosuppressive, this treatment targets the root cause of UC  which is gut dysbiosis, increasing immunity. SER-287 clinical trial is currently recruiting participants if you are interested; contact information is below.

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Do microbiomes on drugs look healthy? Biologics & PPI

Summary:  I’ve wondered literally for years now, ever since I first learned of the microbiome, do microbiomes on drugs look healthy?  I call it the “drugged microbiome,” and I (foolishly perhaps) expect the drugged microbiome to look like a “healthy microbiome”  since this is where 80 to 85% of our immune status resides.  We already know that ~60 drugs are known to be affected by the microbiome  though researchers suspect the real number is much higher.  My question turns this on it’s head and asks, 

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SCD thoughts given DrOz 3 Day Cleanse, Microbiome

SUMMARY:  Finally! A peek into our trillions of innards on a 3 day fruit and vegetable blitz!  Spoiler alert:  There is NOT much impact 10 days after stopping that 3 day cleanse, microbiome resulting from healing diet tenets persist!  

And that, I think, is the lesson to be learned for the healing diets such as SCD, GAPS, PALEO, AIP, WAHLs, to name a few.  Realize, the tenets of these healing diets are for everyone if you want to prevent chronic disease, not just those with chronic disease.  These protocols increase vegetables and fruits beyond what the normal Standard American Diet (SAD) yokel is consuming and adds in healthy fats so fat soluble vitamins are actually absorbed.  This is done concomitant with ditching processed foods,  including processed sugars, and other inflammatory foods.  How powerful are these tenets?  They are healing and inducing remission in messed up impoverished gut microbiomes, and some of those folks are only 80% compliant with the diet!  Nuff said.  Shouldn’t you know what these tenets are?

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50 IBD SCD remission patients: RUSH paper

SUMMARY:  In August, 2015, RUSH University published  their study of 50 IBD Specific Carbohydrate Diet (SCD) remission patients: The Specific Carbohydrate Diet for Inflammatory Bowel Disease: A Case Series. This is the largest report on a series of patients with IBD following the SCD to date and describes their clinical characteristics.  50 patients in remission eating SCD case series are reported which comprise: 36 subjects had Crohn’s Disease, 9 subjects had Ulcerative Colitis, and 5 subjects had in-determinant IBD.  

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Home test finds gut inflammation before relapse (3 months prior)

SUMMARY:  Imagine a home test differentiating between Irritable Bowel Syndrome (IBS) and autoimmune Inflammatory Bowel Disease (IBD)! The time is nearing…  IBdoc is a cheap easy to use home test that measures gut inflammation and presently is used in Europe.  It is still 2 to 3 years away from FDA approval in the US, but clinical trial recruitment has begun; make the call and participate (see below for details.) The device finds gut inflammation before relapse or flare: actually 3 months ahead of IBD relapse giving you (and your physician) time to address such.  The device hopefully too will be found capable of differentiating between IBD versus IBS.  Update: tweeted from 11th Congress of ECCO March 16-19, 2016 presentation: fecal calprotectin rises 4 months before flares. 

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Preserve & Restore Loss of Microbiome Diversity is Aggressive Preventative Medicine

SUMMARY:  Aggressive Preventative Medicine means preserving the microbiome you have and restoring any loss incurred.  See how far that thought goes with your doctor!  Diet really does work to alter the microbiome and can help to restore loss of microbiome; for example, fermented kimchi actually positively impacted metabolic syndrome factors including systolic and diastolic blood pressures, percent body fat, fasting glucose, and total cholesterol.  

⇒⇒  This post teaches how to reduce the loss of microbiome diversity and restore such – crowding out concept.

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