Category Archives: Blog: Autism

IBS, Microbiome, Fodmaps, Probiotics

SUMMARY:   Bottom Line of this post: You want OFF the IBS diseasepan!  WHY? Because — putting aside pain, bowel issues, and bloat — IBS can alter the brain size and function in the emotion and sensory processing areas when having it a long time along with early life stressors [Labus et al., 2017], it is associated with a lot of diseases, and there are a lot of surgeries performed inappropriately because of misdiagnosis or poor manangement of IBS!  DISEASES associated with IBS — it is not comprehensive: Type 2 Diabetes, metabolic syndrome, fibromyalgia, chronic fatigue syndrome, IBD, CFS/ME, autism, anxiety, depression, MS, and Parkinson’s.  Inappropriate SURGERIES occurring due to IBS  misdiagnosis —  appendectomy, cholecystectomy, ovarian, and hysterectomy.  See below for All of those links. There are lots of ways to get off the IBS diseasespan!  Learn in this post that it is YOUR choice:  IBS, Microbiome, Fodmaps, Probiotics, Mindfulness-based stress reduction, Cognitive behavioral therapy works… or targeted drugs!  Or not drugs — the efficacy of that current US standard of care:  “The physician should also emphasize the chronic nature of this syndrome [IBS] because nearly 75% of patients continue to have a diagnosis of IBS 5 years later.13  [Occhipinti et al., 2012].   Many different drugs have been suggested for IBS treatment, but their real benefits are very debatable.”  [Bellini et al., 2014].   Don’t be surprised.  In 2012, the FDA changed the endpoints of those drug studies to stop being only one endpoint because of how multi factorial IBS symptomolgy is, and the Bristol Stool Chart — defining what is a ‘normal BM’ (which you’ll learn in this post) — despite being around since 1997, is only now being validated, 2016!  Contrast all this to the UK British Dietetic Association guidelines for IBS — low FODMAP diet is the second-line intervention [Catassi et al., 2017]  [McKenzie et al, 2016]   [UK evidence-based practice guidelines for dietetic management of IBS in adults 2012 PDF]) as it helps about seventy-six percent of IBS patients  [Magge et al., 2012]  [Bohn et al., 2015]   [Staudacher et al., 2011] and yet, it has come under attack with the current US standard of care still NOT recognizing the FODMAP diet (see this post).  A rebuttal to all the rift recently published in 2017, authored by Monash University ressearchers, the creators of the FODMAP diet.  See  [Hill et al., 2017]  To piggyback the diet fix, studies continue to find that probiotics might be something to think about for some cases of IBS — see  [Whiteley, 2016].  Wondering about IBS and what early life stressors might mean?  That group had more history of early life trauma (general trauma (31 items), physical (9 items), emotional (7 items), and sexual abuse (15 items)) AND they had longer duration of IBS symptoms.  [Labus et al., 2017]  While we can’t change our early life stressors, there are lots of ways to tackle IBS using diet, probiotics, mindfulness-based stress reduction, cognitive behavioral therapy and targeted drugs — according to the Monash rebuttal [Labus et al., 2017].  Now you know!  Protect brain size and function, avoid potentially needless surgery and improve your disease status by fixing IBS; LISTEN to your gut!  Unbelievable… check out the global prevalence of IBS:

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Study Recruiting for Antibiotics, Autism Symptoms

Summary:  The 2014 1st International Symposium on the Microbiome in Health and Disease with a Special Focus on Autism brought out anecdotal parent findings that autism symptoms improved or worsened on antibiotics.  Baylor College of Medicine study in conjunction with Texas Children’s Hospital, is now investigating those findings!  If you have an autistic child, consider enrolling now before they are sick, so you have a test kit if prescribed an antibiotic over the next two years.  You would send microbiome samples pre and post the antibiotic.  Those are to be evaluated for changes to behavior and the microbiome — the bacteria, yeasts and fungi that also inhabit the gut, as well as examining metabolites (small chemical molecules) found in the GI tract. The study is free to participants and fully paid for by N of One: Autism Research Foundation which is founded by John Rodakis, the father of an autistic son who experienced symptom improvement due to an antibiotic dose Thanksgiving 2012.  Participate if you can to increase understanding of Antibiotics, Autism Symptoms which at present, has a gap in the published autism research. This initial data may more effectively sub-type autism and develop and deliver more effective microbial-based interventions.

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IBD CAM, LDN, probiotics, SCD… & Integrative Medicine benefits gut health

SUMMARY:   IBD CAM “Probiotics, Special Diets [SCD], and Complementary Therapies:  We Know Patients Want Them, So What Do We Tell Them? was presented at the Dec. 2014  Advances in IBD conference, by Dr. Sandra Kim, MD, who noted, “SO CERTAINLY THERE IS SOME PROMISE IN AT LEAST THINKING ABOUT THIS.”  Now that’s a first!!!  At least one conventional doctor is encouraging her peers to  seriously educate themselves about IBD CAM, LDN, probiotics, SCD… and  Integrative  Medicine and to ask their patients if they are interested in them, using them and if so, what do they use, and to actively seek funding for further study of them!  And… Dr. Kim has disclosure of conflicting interests — Speaker: Nestle NutritionAbbott Laboratories and Consultant: AbbVie Pharmaceuticals!

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Roundup in our food glyphosate and disease: autism, diabetes, Alzheimer’s, diabetes, gmo, intestinal gut…

SUMMARY:  Roundup on your yard means runoff in your garden, from you or your neighbors use.  It’s ubiquitous in the restaurant and grocery food chain hidden in ingredients: corn, soybeans, canola, and cottonseed oil, and meat from alfalfa-corn-soy eating animals and their other byproducts. It’s found in our urine and breast-milk and cattle’s tissues: intestine, liver, muscle, spleen, kidney, and bone .  

What’s the harm of eating ubiquitous glyphosate?  Glyphosate and disease: autism, diabetes, Alzheimer’s, and the gmo intestinal gut having related digestive system disorders leading to disease… In simpleton, glyphosate exposure impairs detox pathways through the microbiome including the liver’s P450 enzymes. Toxins taken onboard are not sufficiently eliminated from the body. Gyphosate kills beneficial gut bacteria allowing pathogens to grow; it interferes with the synthesis of amino acids including methionine which leads to shortages in critical neurotransmitters and folate; it chelates (removes) important minerals like iron, cobalt, manganese, and much more.

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A professional autism dietary intervention program.

Summary:  It is time to share what a successful professional autism dietary intervention program can look like for autism management.

“Special Diets and Nutrition For Autism: Why They’re Cost Effective,” is such an interesting read from Judy Converse MPH RD LD, a registered dietitian since 1989, who then self taught herself, beginning in 1996, diet impact for her son’s growth, feeding, and developmental challenges at birth.   She then expanded training to learn biomedical intervention for autism, becoming a DAN practitioner, and ultimately provided instruction in nutrition for Autism Research Institute, US Autism and Aspergers Assocation, National Autism Association, and many others. She has lectured for many local and national audiences about the profound impact nutrition and a healthy gut have on the developing brain as well as authoring three books and created the first web-interface accredited learning module for health care providers on nutrition and autism in 2007.

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Crowd Sourcing DNA Sequencing for Autism

“Lots of things are mysteries. But that doesn’t mean there isn’t an answer to them. It’s just that scientists haven’t found the answer yet.   – Christopher John Francis Boone, “If you put 10,000 people’s genomes in the cloud, could you demystify autism?”

It’s happening!   Cancer and autism is leading the way “Medicine will soon rely on a kind of global Internet-of-DNA which doctors will be able to search on Goggle’s cloud platform. “Our bird’s eye view is that if I were to get lung cancer in the future, doctors are going to sequence my genome and my tumor’s genome, and then query them against a database of 50 million other genomes. The result will be ‘Hey, here’s the drug that will work best for you.’ ”“

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Autism Microbiome Study: 2 Studies Seek Participants

The 1st major funded Autism Microbiome Study:

“Autism Speaks Invests $2.3 Million in Research on Autism Gut-Brain Connection, which makes these studies the first major funded GI initiative that investigates microbiome, biological stress and  bowel  disorder treatment in children with autism.  

Clinical trials will span 3 years and are now filling if you are interested.  Please share this information on Facebook, Twitter, Pinterest… so that others can participate.  While this research might be a decade or so behind what parents know, it’s two decades ahead of our GP and many autism treatment facilities, so it’s needed, it’s important, and I’m very grateful to hear about it.

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Food Managing IBD & AUTISM: The Studies

SUMMARY:  Anytime food choices turns around chronic disease with studies that prove such, that should be an eye opener!  Implementing principles of such diets should be considered for anyone wanting to prevent or manage chronic disease.  This post presents studies for Food Managing IBD & AUTISM, where dietary protocols achieved remission and management (with reduction, if not elimination of medication) for autoimmune IBD , or positively altered the course of autism.

HOW?  Diet can optimize (or modulate) the gut microbiome which is the source of 80 – 85 percent of our immunity:  

The “1st International Symposium on the Microbiome in Health and Disease with a Special Focus on Autism,” July 2014: “the microbiome refers to the constellation of enteric bacteria that create an organ system that makes up 80% of our immune system...

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Digestive Enzymes & Disease w/Focus on Autism

Digestion: we all do it though most take it for granted unaware that improper digestive enzymes and subsequent digestion is the root cause of most disease which is epidemic at the moment:

Disease Epidemic_PNG file
Slide source: biomeonboardawareness.com

Those with digestive dysfunctional symptoms (GERD, heartburn, bloat, gas, bowel Bristol Chart type issues…) don’t take it for granted.  Neither should you.

Any blimp in the digestion trek, from brain to elimination, has upstream and downstream ramifications particularly affecting the microbiome community bacterial species balance.   Most, if not all disease, is now being connected to microbiome community shifts.

This post focuses on autism specifically only because there are many current studies documenting the autism digestion dysfunction.  The overall message however applies to all of us.

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FEED YOUR MICROBIOME TO MANAGE AUTISM

Microbiome and autism…  Feeding your gut microbiome could exacerbate, or modulate, autism symptoms.  That understanding is incredibly empowering to those that must manage autism!

It is now undisputed that the gut microbiome differs in autism compared to healthy controls:

“At the annual meeting of the American Society for Microbiology held in May in Boston, researchers at Arizona State University reported the results of an experiment in which they measured the levels of various microbial by-products in the feces of children with autism and compared them with those found in healthy children. The levels of 50 of these substances, they found, significantly differed between the two groups. And in a 2013 study published in PLOS ONE, Italian researchers reported that, compared with healthy kids, those with autism had altered levels of several intestinal bacterial species, including fewer Bifidobacterium, a group known to promote good intestinal health.”  “Gut Bacteria May Play a Role in Autism”, Scientific American, Aug 2014.  

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