SUMMARY: This is an incredibly timely followup to my last post, ANTIBIOTIC RESISTANCE AND MICROBIOME COMPETITIVE CROWDING OUT CONCEPTS. Copied below is the press coverage, issued just minutes ago, of:
Today: Obama White House Convenes (one day) First Antibiotic Summit focusing on “Forum on Antibiotic Stewardship” .
I can’t say enough about the real risk for acquiring an antibiotic resistant infection as explained in my last post, ANTIBIOTIC RESISTANCE AND MICROBIOME COMPETITIVE CROWDING OUT CONCEPTS, especially given that the average American has lost 1/3 of their diversity. Another study estimates 1 in 4 have 40% less bacteria (see prior post link for references). This post also provided maps that showed individual state antibiotic use and resistance risk:
Antibiotic resistance is an issue that you need to be aware of as antibacterials do not necessarily neutralize these strains. CDiff is one such example, as a virulent, antibiotic-resistant strain of CDiff now causes close to 500,000 new cases and 30,000 deaths a year in the United States alone. –Wide Use of Antibiotics Allows C. Diff to Flourish.
The only cure at the moment is Fecal microbiota transplantation [which] has >90 percent cure for antibiotic resistant CDiff. In the US, only after repeated antibiotic failure (thus confirming that the CDiff strain is in fact antibiotic resistant) is FMT allowed to be administered in order to implant a new donor microbiome. More details can be found in PRESERVE & RESTORE LOSS OF MICROBIOME DIVERSITY IS AGGRESSIVE PREVENTATIVE MEDICINE.
CDiff infections had mainly been thought to be hospital acquired, however, Wide Use of Antibiotics Allows C. Diff to Flourish, and CDC investigates deadly bacteria’s link to doctors’ offices revealed the increased prevalence of infection from “a 2013 study, where researchers found C. diff present in six out of seven outpatient clinics tested in Ohio,including on patients’ chairs and examining tables... patients should wash their hands after visiting the doctor’s office — with soap and water, because alcohol-based gels don’t get rid of C.diff.”
Antibioitics associated with CDiff includes: “Ampicillin, amoxicillin, cephalosporins, clindamycin and fluoroquinolones are the antibiotics that are most frequently associated with the disease, but almost all antibiotics have been associated with infection.” –Wide Use of Antibiotics Allows C. Diff to Flourish
“The healthy gut microbiota has three features: a large number of micro-organisms, a large number of different species, and an increased representation of certain bacterial phyla and a decreased representation of other phyla. The disruption of any of these features can result in increased susceptibility to the growth of C. difficile… Even after infected individuals recover, about 5 percent continue to harbor the toxic strain in their stool for six months, and if they take another antibiotic during that time, the illness can recur.”
No mention of Microbiome Connection to Antibiotic Resistant Infections
Sadly, the White House has left off the Antibiotic Summit table mention of microbiome, as well as of how individuals can best protect themselves from antibiotic resistant infections, which likely is through shoring up a diverse healthy microbiome (see OPTIMAL MICROBIOME DIET FROM AMERICAN GUT DATA for the eleven point punch list from key 16SrRNA researcher Dr. Rob Knight.) I am sincerely glad you understand and appreciate THE SCIENCE BEHIND FOOD, DISEASE, MICROBIOME and it’s impact on health and wellness.
Now for the copy of the press coverage:
Today: Obama White House Convenes First Antibiotic Summit, by Maryn McKenna
Representatives of more than 150 health care organizations, medical schools, pharmaceutical companies federal health agencies and food-production interests will meet at the White House today for a day-long “Forum on Antibiotic Stewardship,” the first of its kind. The Forum is a day-long meeting, to be held mostly out of the public eye, in which the Obama Administration plans to press the companies and organizations to commit to plans to reduce and conserve antibiotic use, in order to slow down the advance of antibiotic resistance.
Putting its own marker on the table, the White House announced this morning that it is directing federal departments to begin purchasing meat and poultry raised with what they called “responsible antibiotic use,” a term that is going to take some unpacking but that probably means in accordance with the reduced-antibiotic use policies that the Food and Drug Administration has been pushing forward since last year. In an announcement posted this morning, the White House said the purchasing plan would have work on a five-year timeline, ending up in 2020 with “applying a preference” for antibiotic-free meats.
The summit follows on a suite of other actions the administration has taken to combat resistance, which according to data from the Centers for Disease Control and Prevention kills 23,000 American each year and sickens more than 2 million. (The UK-based Review on Antimicrobial Resistance estimates that the worldwide toll is 750,000 deaths a year, and predicts it will rise as high as 10 million.) Last year, the administration issued a national strategy for combatting resistance, along with an executive order signed by Obama, and a lengthy report by the President’s Council of Advisors on Science and Technology that set forth explicit steps each agency and the private sector should take.
In a press briefing Monday evening, Amy Pope, the deputy Homeland Security advisor, said the summit today is intended to push those efforts along further, by bringing to the table the entire range of entities involved with any aspect of resistance, and getting them to make explicit (though voluntary) commitments to taking action.
Here are a few of the commitments, according to a White House fact sheet released this morning:
- Hospital Corporation of America: agrees to develop computerized decision-making tools for tracking lab results, highlighting the emergence of resistance in patients, and choosing the best prescriptions;
- Intermountain Healthcare: commits to reducing inappropriate outpatient antibiotic use by half;
- Pediatric Infectious Disease Society: will ensure that hospitals that usually cater to adult patients will have stewardship education tools that address the different care and prescription needs of kid patients;
- BD Diagnostics: will develop rapid tests for CREs, the almost completely resistant superbugs that have been spreading through hospitals across the US for 15 years.
There is likely to be a lot of attention paid to the commitments being made by food-production and food-service companies, because in the push to reduce resistance, agriculture and veterinary pharma have resisted change. On the summit invitation list are a number of food companies that have recently made striking commitments to change their practices, including McDonald’s, Tyson, Walmart, and Smithfield, along with Foster Farms, which just yesterday announced antibiotic reduction policies.
Speaking during the briefing last night, Dr. Thomas Frieden, director of the CDC, said: “Tomorrow is a really important day, because antibiotic resistance is a really important problem.”
I’ll update with ongoing coverage and links throughout the day.
Increased health through your awareness,